Scaling microfluidics for cell manufacture

用于细胞制造的微流体扩展

• 批准号: LP160100570
• 负责人: Dr Robert Nordon
• 金额: $ 16.74万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-09-12 至 2019-09-11
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP160100570
• 关键词: Scaling; microfluidics; cell; manufacture

Scaling microfluidics for cell manufacture. This project aims to scale microfluidic devices for cell manufacture. Large-scale cell manufacturing processes (cell selection, gene transfer and culture expansion) are expensive, multistep and labour-intensive processes. Lab-on-a-chip devices can automate and integrate these complex processes at microscale. This project will evaluate a prototype bioreactor. This research is expected to make cell therapies cheap enough to become standard treatment, which would benefit patients with diseases that are incurable by conventional therapies (surgery and drug treatments). It should also benefit the Australian advanced manufacturing sector, particularly biopharmaceutical and cell therapy industries.

微流体技术在电池制造中的应用。该项目旨在扩大微流体装置用于电池制造。大规模细胞制造过程（细胞选择、基因转移和培养扩增）是昂贵、多步骤和劳动密集型的过程。芯片实验室设备可以在微尺度上自动化和集成这些复杂的过程。这个项目将评估一个原型生物反应器。这项研究预计将使细胞疗法变得足够便宜，从而成为标准治疗方法，这将使患有传统治疗方法（手术和药物治疗）无法治愈的疾病的患者受益。这也将有利于澳大利亚的先进制造业，特别是生物制药和细胞治疗行业。