Engineering Research Equipment Grant: Automation of a Flow Calorimeter

该项目是一个工程研究设备奖，即， 自动化流量热量计的设备。 项目：分子间氢键（H-键）代表一种形式的 分子引力介于物理货车 德瓦尔力和真正的化学键 当它们发生时， 对流体的热物理性质有显著的影响， 因此，对这一现象进行深入研究， 从科学和工程的角度来看。 科罗拉多矿业学院正在进行的研究是一个系统的 研究一类重要材料的键合;五元键合 由芳族（呋喃，噻吩， 吡咯）和非芳族（四氢呋喃，四氢噻吩，和 吡咯烷）种类。 平衡缔合常数（K）和 结合能（WHO）是通过测量热 当缔合物种的稀溶液在 惰性溶剂在流动量热计中被无限稀释。 热量计设施的自动化将增加研究 生产率至少提高50%。 实际意义：本实验结果及今后的研究 对其它更复杂的杂环基团的研究将 大大增加了我们对氢键作用的理解， 芳香族和非芳香族化合物，以及添加到数据库 为开发改进的过程热力学模型 计算。

This project is an award for engineering research equipment, namely, equipment to automate a flow calorimeter. PROJECT: Intermolecular hydrogen bonds (H-bonds) represent a form of molecular attraction intermediate in strength between the physical van der Waal's forces and a true chemical bonding. When they occur, H-bonds have a dramatic effect on the fluid's thermophysical properties, and thus a thorough study of this phenomenon is extremely important from both a scientific and an engineering perspective. The research being conducted at Colorado School of Mines is a systematic study of bonding in an important class of materials; the five-membered heterocyclic ring compounds composed of both aromatic (furan, thiophene, pyrrole) and nonaromatic (tetrahydrofuran, tetrahydrothiophene, and pyrollidine) species. Both equilibrium association constants (K) and bonding energies (WHO) are being determined by measuring the heat effects that occur when a dilute solution of an associating species in an inert solvent is taken to infinite dilution in a flow calorimeter. Automation of the calorimeter facility will increase research productivity by at least 50 percent. PRACTICAL SIGNIFICANCE: The experimental results of this and future investigations of other more complex heterocyclic groups will substantially increase our understanding of H-bonding effects in aromatic and nonaromatic compounds, as well as add to the data base necessary for developing improved thermodynamic models for process calculations.