Acquisition of a High Pressure Liquid Chromatograph (HPLC)

购买高压液相色谱仪 (HPLC)

• 批准号: 8705252
• 负责人: James Sodetz
• 金额: $ 3.5万
• 依托单位: University of South Carolina at Columbia
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-01 至 1991-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8705252&HistoricalAwards=false
• 关键词: Acquisition; Pressure; Liquid; Chromatograph; HPLC

A protein chemistry laboratory will be enhanced by the acquisition of a microbore HPLC; the laboratory also has a amino acid analyzer and an amino acid sequencer. The projects to be supported by the new instrumentation include protein crosslinking by glucose and free radicals, the active site environment of thymidylate synthase, proteins involved in nuclear DNA condensation during spermatogenesis, the role of selenium in biomolecules, the molecular basis for human complement protein interactions, and the proteins involved in electron transport in photosynthetic bacteria. The university will provide salary support as well as capital cost sharing toward the establishment of the protein chemistry laboratory.

获得微孔高效液相色谱法将加强蛋白质化学实验室；本实验室还设有氨基酸分析仪和氨基酸测序仪。新仪器将支持的项目包括葡萄糖和自由基的蛋白质交联、胸苷酸合成酶的活性位点环境、精子发生过程中参与核DNA凝聚的蛋白质、硒在生物分子中的作用、人类补体蛋白相互作用的分子基础。光合细菌中参与电子传递的蛋白质。该大学将为建立蛋白质化学实验室提供工资支持和资本成本分担。