MRI: Acquisition of a Liquid Chromatograph-Ion Trap Mass Spectrometer with Electrospray/Atmospheric Pressure Chemical Ionization to Support Faculty-Student Research
MRI: Acquisition of a Liquid Chromatograph-Ion Trap Mass Spectrometer with Electrospray/Atmospheric Pressure Chemical Ionization to Support Faculty-Student Research
批准号:
0320738
负责人:
Paul Jackson
金额:
$20.2万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-09-01 至 2006-08-31
中文摘要
有了这个奖项从主要研究仪器(MRI)计划,化学系在圣奥拉夫学院将获得液相色谱-离子阱质谱仪(LC/MS)与电喷雾/大气压化学电离。这一设备将加强若干领域的研究,包括:a)研究农业地区地表水系统中治疗剂、代谢物、个人护理产品及其降解产物的丰度和结构形式;和B)开发与生物化学组合合成相结合的分析方法,目的是了解一系列化学结构如何影响受体结合位点。 液相色谱-质谱检测(LC/MS)是一种非常强大的技术,用于分离和分析复杂的混合物。这一工具将大大加强圣奥拉夫学院的科学研究,该学院主要是本科院校。 这些研究将在环境化学和生物化学领域产生坚实的影响。
英文摘要
With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Saint Olaf College will acquire a liquid chromatograph-ion trap mass spectrometer (LC/MS) with electrospray/atmospheric pressure chemical ionization. This equipment will enhance research in a number of areas including a) studies on the abundance and structural forms of therapeutic agents, metabolites, personal care products and their degradation products in surface water systems located in agricultural areas; and b) analytical methods development combined with biochemical combinatorial synthesis with a goal towards understanding how an array of chemical structures influence receptor binding sites. Liquid chromatography with mass spectrometric detection (LC/MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at the Saint Olaf College, a primarily undergraduate institution. These studies will have a solid impact in the area of environmental chemistry and biochemistry.
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