MRI: Acquisition of a Liquid Chromatograph-Ion Trap Mass Spectrometer with Electrospray/Atmospheric Pressure Chemical Ionization to Support Faculty-Student Research

MRI：购买具有电喷雾/大气压化学电离功能的液相色谱-离子阱质谱仪，以支持师生研究

• 批准号: 0320738
• 负责人: Paul Jackson
• 金额: $ 20.2万
• 依托单位: Saint Olaf College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0320738&HistoricalAwards=false
• 关键词: MRI; Acquisition; Liquid; Chromatograph; Ion

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Saint Olaf College will acquire a liquid chromatograph-ion trap mass spectrometer (LC/MS) with electrospray/atmospheric pressure chemical ionization. This equipment will enhance research in a number of areas including a) studies on the abundance and structural forms of therapeutic agents, metabolites, personal care products and their degradation products in surface water systems located in agricultural areas; and b) analytical methods development combined with biochemical combinatorial synthesis with a goal towards understanding how an array of chemical structures influence receptor binding sites. Liquid chromatography with mass spectrometric detection (LC/MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at the Saint Olaf College, a primarily undergraduate institution. These studies will have a solid impact in the area of environmental chemistry and biochemistry.

圣奥拉夫学院化学系获得重大研究仪器(MRI)项目的这一奖项后，将获得一台带有电喷雾/大气压化学电离的液体色谱仪-离子陷阱质谱仪(LC/MS)。该设备将加强若干领域的研究，包括：a)研究农业地区地表水系统中治疗剂、代谢物、个人护理产品及其降解产物的丰度和结构形式；b)结合生物化学组合合成开发分析方法，目的是了解一系列化学结构如何影响受体结合部位。液质联用(LC/MS)是一种用于复杂混合物分离和分析的非常有效的技术。该仪器将大大加强圣奥拉夫学院的科学研究，圣奥拉夫学院主要是一所本科院校。这些研究将在环境化学和生物化学领域产生坚实的影响。