U.S.-France Cooperative Research: Dynamics of Water in Supercooled States in Bulk, in Reverse Micelles and in Proteins

美法合作研究：水在过冷状态下的散装、反胶束和蛋白质动力学

• 批准号: 8715085
• 负责人: Sow-Hsin Chen
• 金额: --
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-02-15 至 1992-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8715085&HistoricalAwards=false
• 关键词: U.S.; France; Cooperative; Research; Dynamics

This award will support collaborative research between Professor Sow-Hsin Chen of the Massachusetts Institute of Technology, and Dr. Jose Teixeira of the Laboratoire Leon-Brillouin of the Centre d'Etudes Nucleaires, Saclay, France. The objective of this work is to study the microscopic structural and dynamic properties of bulk supercooled water, which differ from those of normal water, using techniques of thermal neutron and X-ray diffraction, and quasi-elastic and inelastic neutron spectroscopy. In addition, the dynamics of water in confined geometries, as in the interior of reverse micelles and in certain types of molecules at low temperatures, will be studied. In these systems, the interaction of the water with the proximate surfaces is important in understanding the folding and enzymatic activity of water and similar macromolecules. The study will also be extended to include other super-cooled liquids near their freezing or transition-to-glass temperatures. The instruments for the high resolution neutron spectroscopy measurements are available only in France. This research may have important applications in the fields of chemical reactions and cooling-system behavior.

该奖项将支持合作研究， 马萨诸塞州研究所的陈索欣教授 技术和何塞特谢拉博士的技术 里昂-布里渊研究中心教授 Nucleaires，Saclay，法国. 的目的 工作是研究微观结构和 大体积过冷水的动力学性质， 与普通水不同， 热中子和X射线衍射， 准弹性和非弹性中子能谱。 在 此外，还研究了承压水的动态 几何形状，如在反胶束的内部， 在低温下的某些类型的分子中， 将被研究。 在这些系统中， 水与邻近表面是重要的， 了解蛋白质的折叠和酶活性 水和类似的大分子。该研究还将 可以扩展到包括其他过冷液体附近 它们的冻结或玻璃化转变温度。 高分辨中子测量仪器 光谱测量仅适用于 法国 这项研究可能有重要的应用 在化学反应和冷却系统领域 行为