The Role of Glycopeptide and Peptide Antifreezes in FreezingAvoidance of Antarctic Fishes

南极鱼类在远低于体液正常冰点的温度下，在冰封的海水中抵抗冰冻的能力，是适应极地条件的主要能力之一。德弗里斯计划领导一个跨学科团队，研究防冻剂在防止冰晶在肠液中繁殖的作用，防冻剂与冰相互作用的生物物理学，以及防冻剂基因的分子生物学和组织。提供抗冻能力的机制的性质具有重要的进化和生态意义。此外，对防冻系统的持续研究应该会揭示冰晶生长的新方面，这可能会对结晶学、成核理论、医学、玻璃化和冷冻食品技术产生影响。

The capacity of Antarctic fishes to resist freezing in ice-laden seawater at temperatures well below the normal freezing point of body fluids represents one of the major adaptations to polar conditions. DeVries plans to lead an interdisciplinary team in studies on the function of antifreezes in preventing the propogation of ice crystals in the intestinal fluid, the biophysics of antifreeze-ice interactions, and the molecular biology and organization of the antifreeze genes. The nature of the mechanisms which provide freezing resistance are of great evolutionary and ecological importance. In addition, continued studies of the antifreeze system should reveal new aspects of ice-crystal growth which could have implications for crystallography, nucleation theory, medicine, vitrification, and frozen-food technology.