Polynuclear Transmetalation Reactions and Products

该奖项由无机，生物无机和有机化学 化学计划是在过渡金属化学领域。 该项目关注的是两个原子的反应， 不同的金属在载体分子之间交换， 即所谓的金属转移反应。 特别感兴趣的是涉及多金属的反应， 物种，物种包含几个金属原子在一个 分子。该项目的目的之一是利用transmetalation 合成含有原子的多金属物质的反应 一个分子中含有两种或两种以上不同的金属。等 混合金属多金属物种预计将有 有趣的催化性能，也是 重要的酶，如呼吸酶细胞色素 氧化酶。也可以分解混合金属 产生不能直接制造的合金类型 从组成金属。 该项目的重点将是新发现的 金属转移现象， 多金属靶中金属中心的逐步置换 被其他金属从简单的分子transmetalators。的 反应在温和条件下进行，产物 很容易分开。研究的主要组成部分将是： 1)分离、结构表征和电化学 阳离子靶点和金属转移产物的研究; 2)早期重元素迁移作用研究 3）开发和使用更经济的 transmetalators; 4）识别的连锁反应 transmetalator，产生大的多金属分子; 5） 的选择性配体化学的描述 杂多金属分子; 6）使用金属转移， 产生新的块体合金和负载型金属催化剂;以及7） 杂多金属有机化学的发展。

This award from the Inorganic, Bioinorganic and Organometallic Chemistry Program is in the area of transition metal chemistry. The project is concerned with reactions in which atoms of two different metals are exchanged between carrier molecules to which they are attached, so-called transmetalation reactions. Of particular interest are reactions involving polymetallic species, species which contain several metal atoms within one molecule. One aim of the project is to use transmetalation reactions to synthesize polymetallic species containing atoms of two or more different metals within one molecule. Such mixed-metal polymetallic species are expected to have interesting catalytic properties and also are models of important enzymes, such as the respiratory enzyme cytochrome oxidase. It may be possible also to decompose the mixed-metal species to yield alloys of types which cannot be made directly from the constituent metals. The focus of the project will be the newly discovered phenomenon of transmetalation which leads to quantitative, stepwise replacement of metal centers in polymetallic targets by other metals from simple molecular transmetalators. The reactions proceed under mild conditions and the products are easily separated. The major components of the research will be: 1) isolation, structural characterization and electrochemical studies of cationic targets and transmetalation products; 2) investigation of earlier and heavier element transmetalation systems; 3) development and use of more economical transmetalators; 4) identification of reactions of linkage transmetalators which give large polymetallic molecules; 5) description of the selective ligand chemistry of heteropolymetallic molecules; 6) use of transmetalation to generate new bulk alloys and supported metal catalysts; and 7) development of heteropolyorganometallic chemistry.