Transport Characteristics of Renal Tubules of the Avian Kidney

该提案描述了将试图 阐明转运功能（即重吸收）的细节 从尿液到血液）在鸟类肾脏中。 这样的细节， 脊椎动物群直到最近才有所发现。 鸟 肾脏在形态上看起来像是 爬行动物和哺乳动物。 这使得鸟肾 有趣的模型研究的适应性特点的两个 肾脏类型 此外，鸟类的肾脏似乎拥有 某些运输特征可能是脊椎动物所独有的， 因此，可能为细胞多样性提供新的见解， 功能 这项工作将专门使用显微穿刺和 研究液体和电解质的电生理技术 在浅表的“爬行动物型”肾单位中运输。 在 此外，运输活动的激素调节将是 研究了

This proposal describes experiments that will attempt to elucidate details of the transport functions (i.e. reabsorption from urine to blood) in the avian kidney. Such details for this vertebrate group have been lacking until recently. The bird kidney appears morphologically like a hybrid of kidneys found in reptiles and in mammals. This makes the bird kidney an interesting model for study of the adaptative features of the two kidney types. In addition, the avian kidney appears to possess some transport features that may be unique among vertebrates, and may therefore provide new insight into cellular diversity of function. This work will specifically use micropuncture and electrophysiological techniques to study fluid and electrolyte transport in superficial, "reptilian-type" nephrons. In addition, hormonal regulation of transport activity will be studied.