Crystal Purity Habit and Size Distribution from Batch Crystallization

批量结晶的晶体纯度习性和尺寸分布

• 批准号: 8722281
• 负责人: Ronald Rousseau
• 金额: $ 21.68万
• 依托单位: Georgia Tech Research Corporation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-01-01 至 1992-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8722281&HistoricalAwards=false
• 关键词: Crystal; Purity; Habit; Size; Distribution

Crystallization is an important process for producing high-value fine and specialty chemicals, biochemicals and pharmaceuticals. The process remains, however, as an art rather than science. The proposed research is aimed at establishing a scientific basis for the process. The crystallization of four model amino acids will be studied in both batch and continuous crystallizers. An understanding will be obtained for the mechanism of crystal nucleation and growth. The results will have direct impact on the field of crystallization and also expanding its application to bioseparation and purification.

结晶是生产高附加值精细化工产品的重要工序 以及特种化学品、生物化学品和药品。 的 然而，过程仍然是一门艺术，而不是科学。 拟议 研究的目的是为这一进程奠定科学基础。 四个模型氨基酸的结晶将在两个研究 间歇和连续结晶器。 我们会达成共识的 晶体成核和生长的机理。 结果将 对结晶领域有直接影响， 其在生物分离和纯化中应用。