ABR: Molecular Phylogenetic Studies of Select Amphibians

ABR：选定两栖动物的分子系统发育研究

• 批准号: 8722508
• 负责人: Linda Maxson
• 金额: --
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-06-01 至 1988-07-01
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8722508&HistoricalAwards=false
• 关键词: ABR; Molecular; Phylogenetic; Studies; Select

In an Accomplishment-Based Renewal, Dr. Linda Maxson will continue her productive investigations of the phylogenetic relationships of select groups of amphibians, emphasizing especially the hylid and myobatrachid frogs of the world. To analyze the evolutionary divergences among these species, Dr. Maxson estimates the amino acid differences in serum albumin proteins, using a serological technique known as micro-complement fixation. The amino-acid differences have been shown to provide reliable genomic markers of evolutionary descent. In comparisons between species separated by geographic or geological barriers of known geological age (for example, the Straits of Gibraltar), estimates will also be made of the timing of evolutionary events, thus enabling a test of the idea of a molecular albumin clock. Finally, Dr. Maxson will capitalize on a gift of serological antisera from a study of crocodiles (reptiles, not amphibi- ans) to compare results from two different serological methods in estimating phylogenetic patterns.

在基于成就的更新中，琳达·麦克森博士将继续对选定的两栖动物群体的系统发育关系进行富有成效的研究，特别强调世界上的青蛙和肌蛙。 为了分析这些物种之间的进化差异，Maxson 博士使用一种称为微补体固定的血清学技术估计了血清白蛋白中的氨基酸差异。 氨基酸差异已被证明可以提供可靠的进化血统基因组标记。 在对被已知地质年龄的地理或地质屏障（例如直布罗陀海峡）分隔开的物种进行比较时，还将对进化事件的时间进行估计，从而能够测试分子白蛋白时钟的想法。 最后，麦克森博士将利用鳄鱼（爬行动物，而不是两栖动物）研究中提供的血清学抗血清来比较两种不同血清学方法的结果，以估计系统发育模式。