International Symposium on the Molecular Biology of Hydrogenase

第二届氢化酶国际研讨会将于1988年9月19日至23日在北乔治亚州的会议中心Unicoi举行。上一次正式会议是在1985年举行的，此后取得了重大进展。会议由伦纳德·摩顿森博士主持。组委会由博士组成。Harry Peck， Mike Johnson和Jean LeGall，他们都来自乔治亚大学。除报告当前状态外；将作出坚定的努力，设法建立一个资料数据库。将鼓励思想的交流和联合试验。这种酶，氢化酶，对于厌氧生物的生存是必不可少的，因为它将关键还原电子载体的氧化与质子的还原结合在一起，而产生的H又被其他生物用作电子源，例如甲烷菌和硫酸盐还原细菌分别作为CO和硫酸盐还原的电子源。在许多生物体中，氢化酶的功能是已知的，但在其他生物体中，其功能尚不清楚。似乎需要氢化酶利用固氮过程中释放的氢。氢化酶还在多种原核生物中起作用，这些原核生物在地球化学调节中起重要作用。它是一种重要的酶，强烈建议召开一次会议，专门阐明它在自然界中的作用。这些资金将专门用于年轻的研究人员。

The Second International Symposium on Hydrogenase will be held September 19th to the 23rd, 1988 at Unicoi, a conference Center in Northern Georgia. The last formal conference was held in 1985 and substantial progress has been made in the ensued time. The conference is being chaired by Dr. Leonard Mortenson. The organizing committee is composed of Drs. Harry Peck, Mike Johnson and Jean LeGall, all at the University of Georgia. Other than reporting the current status; a determined effort will be made to initiate ways to put together a data base of information. A cross fertilization of ideas and joint experimentation will be encouraged. The enzyme, hydrogenase, is essential for the survival of anaerobic organisms since it couples the oxidation of key reduced electron carriers to the reduction of protons, and in turn the H produced is used as an electron source by other organisms, such as the electron source for CO and sulfate reductions by methanogens and sulfate reducing bacteria, respectively. In many organisms the function of the hydrogenase is known but in other organisms the function is unclear. It appears hydrogenase is required to use the H released during nitrogen fixation. Hydrogenase also functions in a variety of procaryotes that are important in geochemical regulation. It is an important enzyme and a meeting dedicated the elucidation of its role in nature is strongly recommended. These funds will be targeted for young investigators.