Equipping an Undergraduate Instructional Laboratory with theTools of the Molecular Biologist.

为本科生教学实验室配备分子生物学家的工具。

• 批准号: 8750842
• 负责人: Rivka Rudner
• 金额: $ 4.52万
• 依托单位: CUNY Hunter College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-05-01 至 1989-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8750842&HistoricalAwards=false
• 关键词: Equipping; Undergraduate; Instructional; Laboratory; theTools

Recent advances in Molecular Biology and Molecular Genetics are significantly changing the laboratory approaches required for training undergraduates majoring in Biology. The Hunter College faculty has prepared a revised and expanded one-year Molecular Biology course for undergraduate majors which includes two updated laboratory courses in the areas of Biochemistry and Molecular Genetics. The revised and expanded curriculum (emphasizing basic cloning techniques, analysis of the plasmids present in recombinant clones, isolation and characterization of enzymes, and structural analysis of cell surfaces) will give students increases hands-on laboratory experience with molecular procedures and scientific instruments. In addition, increased access to the course for students with limited experience in the tools of scientific investigation will be possible. For the experienced students there is opportunity to expand their existing knowledge by using modern molecular techniques for an independent honors research project. Additional changes in the two laboratory courses are also projected with the utilization of this same equipment. The major items being used to implement these changes include high speed ultra- and micro-centrifuges, a scintillation counter, shaker incubator and a speed-vac system. A large fraction of the students benefitting from these courses are women and/or members of minority groups underrepresented in the Nation's pool of scientists.

分子生物学和分子遗传学的最新进展极大地改变了培养生物学专业本科生所需的实验室方法。亨特学院的教师为本科专业准备了一个经过修订和扩展的为期一年的分子生物学课程，其中包括生物化学和分子遗传学领域的两个更新的实验课程。修订和扩展的课程（强调基本的克隆技术，重组克隆中存在的质粒分析，酶的分离和表征，以及细胞表面的结构分析）将使学生增加对分子程序和科学仪器的动手实验室经验。此外，对于科学研究工具经验有限的学生，可能会有更多的机会学习这门课程。对于有经验的学生，有机会通过使用现代分子技术进行独立的荣誉研究项目来扩展他们现有的知识。在这两门实验课程的其他变化也预计使用相同的设备。用于实现这些变化的主要项目包括高速超微型离心机、闪烁计数器、摇床培养箱和快速真空系统。从这些课程中受益的学生中有很大一部分是女性和/或在美国科学家队伍中代表性不足的少数群体的成员。