Research Initiation: Species Transport Across Polymerized Vesicle Membranes

本项目的目标是审查运输率， 聚合物作为评估使用合成 聚合囊泡作为分离媒介物， 稀溶液中的物种。 该公司享有的独特优势是， 聚合囊泡的另一个特点是它们的膜非常薄，通常 5纳米。 因此，物种迁移率可以大大降低。 增强 本工作将处理两个具体问题： 聚合对膜渗透性的影响;以及 结合具有保留的功能性的化学载体 聚合囊泡膜中的活性。 标记示踪剂 技术将用于研究膜渗透性。 标记 将进行泄漏测试，以评估 聚合的囊泡后，纳入化学载体。 聚合物膜中的化学载体的活性将是 与单体膜相比。 囊泡在药物领域具有相当大的研究兴趣 输送、分离技术、太阳能转换、催化、 和化学传感。 该项目的运输结果将 建立聚合物研究的长期框架 囊泡作为分离车辆在上坡主动运输模式。

The objective of this project is to examine the transport rate in polymers as a means of assessing the feasibility of using synthetic polymerized vesicles as separation vehicles to concentrate selected species from dilute solutions. The unique advantage enjoyed by the polymerized vesicles is that their membranes are very thin, typically five nanometers. As such, the species transport rate can be greatly enhanced. Two specific issues will be addressed in this work: the effect of polymerization on membrane permeabilities; and the incorporation of chemical carriers with preserved functional activities in polymerized vesicles membranes. The labeled tracer technique will be used to study the membrane permeability. Marker leakage tests will be conducted to evaluate the stability of polymerized vesicles after the incorporation of chemical carriers. The activities of chemical carriers in polymeric membranes will be compared with those in monomeric membranes. Vesicles are of considerable research interest in the area of drug delivery, separation technology, solar energy conversion, catalysis, and chemical sensing. The transport results from this project will establish the long term framework for the study of polymerized vesicles as separation vehicles in an uphill active transport mode.