Bioseparations in Multiple Support Magnetically Stabilized Beds

众所周知，足够强的磁场可以抑制可磁极化颗粒的流态化混合。这项研究涉及使用不同的颗粒混合物的磁稳化液体沸腾床的流体力学行为，其中一些颗粒是可磁极化的，用于稳定床层，一些颗粒具有特殊的吸附性能，适合于高效的生化分离过程。床的稳定性将作为颗粒大小、密度和组成、液体速度以及磁场强度和取向的函数进行研究。这项研究还将检查这种床中的蛋白质分离。如果能够实现混合颗粒流态化床的成功稳定运行，将允许在生物化学分离的流态化床操作中获得更大的灵活性，并通过使用已经存在的具有特殊吸附特性的非磁性颗粒立即被行业采用。这项研究还应该提供关于磁场中液体流态化床稳定的有趣信息。

Magnetic fields of sufficient strength are known to suppress mixing in fluidized beds of magnetically polarizable particles. This research concerns the fluid mechanical behavior of magnetically stablilized liquid fluidized beds using various mixtures of particles, some magnetically polarizable for bed stabilization, and some having specific adsorptive properties suitable for an efficient biochemical separation process. Stability of the bed will be investigated as a function of the particle sizes, densities and composition, liquid velocity, and magnetic field strength and orientation. The research will also examine protein separation in such beds. If successful stable operation of mixed particle fluidized beds can be achieved, it would permit greater flexibility in fluidized bed operations for biochemical separations and immediate adoption by the industry through the use of already existing non-magnetic particles having specialized adsorptive properties. The study should also yield interesting information on stabilization of liquid fluidized beds in magnetic fields.