Cooperative Research on Photoaffinic Labelling of Compounds with Pyrene

该奖项支持合作研究， 圣母院的J. Kerry托马斯 智利大学的Andres Olea 在圣地亚哥。 这项工作将涉及光标记 有机（生物）化合物与芘。 等 两所大学都研究了光反应 这项工作始于巴黎圣母院 夫人 该方法将包括 芘，无论是在胆碱区，或接近 甘油或链烷烃链区域， 芘衍生物的制备方法 系统如胶束、囊泡、简单烷烃和 聚电解质 已经使用的技术是快速脉冲动力学， 巴黎圣母院和稳态动力学在智利。 这些 将相辅相成，建立机制， 通过该方法，探针分子：芘、偶氮芘和 叠氮芘与主体形成加成产物 介质 智利的优势在于产品分析， 圣母院的快速脉冲分析 以前的事件。 这一合作将导致 光化学机理的发展 到光化学和胶体社区。

This award supports cooperative research in photochemistry between J. Kerry Thomas of Notre Dame University and Andres Olea of the University of Chile in Santiago. The work will involve the photolabelling of organic (biological) compounds with pyrene. Such photoreactions have been studied at both universities with this specific work having its start at Notre Dame. The approach will include the location of the pyrene, whether in the choline region, or close to the glycerol or to the alkane chain region and also the production of derivatives of pyrene for probing other systems such as micelles, vesicles, simple alkanes and polyelectrolytes. Techniques already in use are fast pulse kinetics at Notre Dame and steady state kinetics in Chile. These will complement each other to establish the mechanisms by which the probe molecules: pyrene, azopyrene and azidopyrene form the addition products with the host medium. Chile's strength is in product analysis and that of Notre Dame is in fast pulse analysis of earlier events. This cooperation will lead to the development of photochemical mechanisms of great use to the photochemical and colloid community.