U.S.-Brazil Cooperative Research: Calcium Transport Across Biological Membranes

该奖项支持生物物理学的合作研究 将由哥伦比亚大学的朱塞佩·伊内西主持， 位于巴尔的摩的马里兰州和 巴西里约热内卢的联邦大学。 的 主题是钙在生物体内的转运 膜。 具体目的是澄清 膜囊泡钙摄取机制 从肌肉组织中提取。 生物 研究的意义在于 肌肉纤维的收缩和松弛。 化学 意义在于理解酶动力学， 催化，催化与传递耦合 活性、通道和跨膜流动 电解质和蛋白质的结构。 长期以来， Inesi博士和几位巴西人之间的合作 科学家们，作为博士后， 在他的实验室里呆了很长时间。 这 赠款将允许继续这一 合作，并加强Inesi博士参与 在巴西的工作。 两位调查员都很好 合格，并将开展工作的重要 这是一个重要的研究领域的问题。

This award supports cooperative research in biophysics to be conducted by Giuseppe Inesi of the University of Maryland at Baltimore and Leopoldo de Meis of the Federal University in Rio de Janeiro, Brazil. The topic is calcium transport across biological membranes. The specific aim is to clarify the mechanisms of calcium uptake in membrane vesicles obtained from muscle tissue. The biological significance of the research is related to the contraction and relaxation of muscle fibers. Chemical significance lies in understanding enzyme kinetics and catalysis, the coupling of catalytic and tranport activities, channels and transmembrane flow of electrolytes and the structure of proteins. There has been a long-standing, productive collaboration between Dr. Inesi and several Brazilian scientists who, as postdoctoral associates, have spent extended periods of time in his laboratory. This grant will allow for the continuation of this cooperation and enhance Dr. Inesi's participation in the work in Brazil. Both investigators are well qualified and will carry out work on an important problem in a vital area of research.