Effect of Peroxide Pre-oxidation on Microbial Degradation of Toxic Wastes

这是美国国家科学基金会女性研究机会奖下的职业发展奖。这项研究的目的是研究诱导氧化在有毒化学品生物降解处理之前的作用。选择了三种主要的模型毒素进行研究，原因是它们的流行率、组成和预期反应的差异。通过添加过氧化物酶和过氧化氢试剂对过氧化氢氧化进行了研究。针对每种模型化合物，选择有毒废物场地中的微生物进行微生物降解过程。测定了含有和不含有过氧化氢形式的每种模型化合物的生物降解率。预氧化加速生物降解是由这些速率的差异决定的。

This is a Career Advancement award under NSF's Research Opportunities for Women. The objective of the research is to study the role of induced oxidation prior to biodegradation treatment of toxic chemicals. Three prominent model toxins have been chosen for study due to their prevalence, differences in composition, and expected response. Hydrogen peroxide oxidation is studied by adding peroxidase enzyme and hydrogen peroxide chemical. Microbes from toxic waste sites specific for each model compound is selected for the microbial degradation process. Biodegradation rates for each model compound with and without the forms of hydrogen peroxide is determined. The acceleration of biodegradation due to pre-oxidation is determined by the difference in these rates.