Purchase of an ORD/CD Spectropolarimeter

购买 ORD/CD 分光旋光计

• 批准号: 8820216
• 负责人: Lawrence Barton
• 金额: $ 5.57万
• 依托单位: University of Missouri-Saint Louis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-01 至 1990-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8820216&HistoricalAwards=false
• 关键词: Purchase; ORD; CD; Spectropolarimeter

The phenomena of Circular Dichroism (CD) and Optical Rotatory Dispersion (ORD) are studied by chemists in order to gain special insight into the specific arrangement of atoms within molecules that possess the property of chirality. A molecule is said to be chiral when it is not superimposable on its mirror image. A crucial instrument used to study the phenomena is the CD/ORD spectropolarimeter. Access to the instrument is essential to those chemists carrying out modern research involving chiral molecules. This award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at the University of Missouri at St. Louis to acquire a CD/ORD spectropolarimeter. The areas of chemical research that will be enhanced by the acquisition include the following: 1) Structure and spectroscopy of high-symmetry aqueous lanthanide complexes 2) Circular dichroism of organo-deuterium compounds 3) Synthesis and structure of chiral thioaryl allenes 4) Detecting conformational changes during iron removal from transferrin 5) Orientation of substrates and active sites in artificial enzymes.

圆二色性和旋光性现象 分散（ORD）是化学家研究，以获得 对原子内部特定排列的特殊见解 具有手性性质的分子。 的分子 当它不能重叠在其上时， 镜像 一种用来研究这些现象的重要仪器 是CD/ORD分光偏振计。 进入仪器是 对于那些进行现代研究的化学家来说， 包括手性分子。 化学共享仪器计划（Chemistry Shared Instruments Program） 将帮助牛津大学化学系 密苏里州在圣路易斯获得CD/ORD分光偏振仪。 化学研究的领域将得到加强， 收购包括以下内容： 1)高对称性水溶液的结构和光谱 稀土配合物 2)有机氘化合物的圆二色性 3)手性硫代芳基联烯的合成与结构 4)检测铁去除过程中的构象变化 铁蛋白 5)人工晶体中底物和活性中心的取向 内切酶