Purhase of a High Resolution Mass Spectrometer

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This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Office of Multidisciplinary Activities (OMA) will assist the Department of Chemistry at University of Missouri at St. Louis to acquire a high resolution mass spectrometer. This equipment will enhance research in a number of areas that include the following: (1) studies on organometallic species used as polymerization catalysts, (2) synthesis and reactions of metallaborane complexes, (3) organic synthesis and development of synthetic methods, (4) natural product isolation and reactions, (5) the analysis of unstable organic oxidation products in simulated environments, and study of self-assembled monolayers derived from modified cyclodextrins. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.