Purhase of a High Resolution Mass Spectrometer

这份来自化学研究仪器和设施（CRIF）项目和多学科活动办公室（OMA）的合同将帮助密苏里大学圣路易斯分校的化学系获得一台高分辨率质谱仪。该设备将加强以下领域的研究：(1)用作聚合催化剂的有机金属物种的研究，(2)金属硼烷配合物的合成和反应，(3)有机合成和合成方法的开发，(4)天然产物的分离和反应，(5)模拟环境中不稳定有机氧化产物的分析，以及改性环糊精衍生自组装单层的研究。质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。电喷雾技术的加入将质谱的范围扩展到蛋白质和核酸分子量，远远超过任何其他技术。电喷雾电离结合高分辨率提供了质谱分析的最新技术。它为化学家提供了表征化合物的最有力的工具之一。在质谱法中获得这种能力对于化学许多领域的前沿研究的进行是必不可少的。

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Office of Multidisciplinary Activities (OMA) will assist the Department of Chemistry at University of Missouri at St. Louis to acquire a high resolution mass spectrometer. This equipment will enhance research in a number of areas that include the following: (1) studies on organometallic species used as polymerization catalysts, (2) synthesis and reactions of metallaborane complexes, (3) organic synthesis and development of synthetic methods, (4) natural product isolation and reactions, (5) the analysis of unstable organic oxidation products in simulated environments, and study of self-assembled monolayers derived from modified cyclodextrins. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.