Equipment Upgrading of Microcomputer Workstation

我们建议更新我们现有的微型计算机技术。 DNA- 蛋白质相互作用是我们理解 DNA复制调控机制，神经胶质细胞 分化和乳腺上皮分化。 我们需要 一个强大的计算机系统来分析数据， 结果以图形方式。 计算机将用于以下方面 a）芽孢杆菌DNA复制的分子生物学 枯草杆菌，研究膜协会的作用， 染色体和质粒复制。B）分子生物学 使用大鼠神经元-神经胶质干的神经元-神经胶质分化 衍生细胞类型，频率约为10-5。 两 其中一种是神经元样细胞，第三种是神经胶质细胞， 比如细胞类型（c）分析增长因素对 乳腺癌细胞系的生长和分化。

We propose to upgrade our current technical microcomputer. DNA- protein interactions are the key for our understanding of the mechanism of regulations of DNA replication, neuronal-glial differentiation and mammary epithelial differentiation. We need a powerful computer system to analyze data and present the results graphically. The computer will be used in the following projects: a) Molecular biology of DNA replication in Bacillus subtilis which studies the role of membrane association of chromosomal and plasmid replication. b) Molecular biology of neuronal-glial differentiation using a rat neuronal-glial stem derivative cell types with an approximate frequency of 10-5. Two of them are neuronal-like cell types and the third is a glial- like cell type. c) Analysis of the effect of growth factors on the growth and differentiation of mammary carcinoma cell lines.