Trigeminal Primary Afferent Organization and Development

大脑是通过感官来感知外部环境的 神经细胞 这些细胞连接到小的感觉器官， 皮肤，另一端，大脑中的神经细胞。 为了让生物体正确理解来自其 环境中，感觉神经细胞必须使适当的 正确的感觉器官和正确的大脑之间的联系 cell. 这个项目将研究这些正确的连接是如何 在胚胎发育期间形成。 正常连接 感觉神经细胞和皮肤之间的联系将被改变， 神经损伤后会发生的情况 然后它将 确定了感觉神经细胞的连接如何变化， 皮肤又改变了它们连接的细胞， 个脑袋 这个项目有可能提高我们对 促进神经细胞之间正确连接的机制 在胚胎发育和神经再生过程中 伤后

The brain is made aware of the external environment by sensory nerve cells. These cells connect both to small sense organs in the skin, and, at their other end, to nerve cells in the brain. In order for the organism to properly understand signals from its environment, the sensory nerve cell must make the proper connection between the correct sense organ and the correct brain cell. This project will examine how these proper connections are made during embryonic development. The normal connections between sensory nerve cells and the skin will be modified in a way that would occur after nerve damage. It will then be determined how changes in the sensory nerve cell's connections to the skin in turn changes which cells they connect to in the brain. This project has the potential to improve our understanding of the mechanisms that promote proper connections among nerve cells during embryonic development and during regeneration of nerves after injury.