"In vitro" modeling of the cooperation between oncogenes and tumor suppressors promoting carcinogenesis in pancreatic adenocarcinoma

致癌基因和肿瘤抑制因子之间的合作促进胰腺癌的发生的“体外”模型

• 批准号: 184583
• 负责人: Radulovich Nikolina
• 金额: $ 10.93万
• 依托单位: Ontario Cancer Institute (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-11-01 至 2011-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184583&lang=en
• 关键词: Cell-Cycle Regulation; K-Ras Oncogene; Mouse Models Of Disease; P16/P14 Tumor Suppressor; Pancreatic Cancer Biology; Quantitative Real Time Polymerase Chain Reaction; Shrna And Cdna Lentiviral Gene Expression; Shrna Library Screening; Tumor Biology; Viral

Pancreatic cancer is the fourth leading cause of cancer death in North America with an overall 5 year survival rate of 2-3%. Early detection and chemoprevention are the best strategies to reduce mortality for this cancer type. This would be best achieved

胰腺癌是北美癌症死亡的第四大原因，总体5年生存率为2-3%。早期发现和化学预防是降低这种癌症死亡率的最佳策略。这是最好的办法