Biology Laboratory Equipment to Support Undergraduates' Studies of the Health Problems in Black Americans

正在制定各种课程的实验室练习，以说明与美国黑人主要健康问题有关的基本生物学原理。这些活动包括正常和镰状细胞血红蛋白的电泳，与格雷夫斯病和镰状细胞患者相关的蛋白质的荧光抗体演示，与美国黑人高血压相关的心血管系统活动，以及用于说明糖尿病、乳糖不耐症、葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症。正在建立四个学生站，用于电泳实验、生化研究和显微工作。另外，正在安装两台分析天平、两台pH计、两台变速离心机、一台倒置相显微镜、一台用于课堂演示的荧光相视频显微镜和一台转移罩。高血压研究的能力已经具备。该项目激励所有学生，特别是少数民族，继续努力追求生物医学相关的职业生涯。此外，制定的实验室活动将作为实验室手册提供给其他机构。受资助机构将从非联邦来源获得等额的NSF奖励。

Laboratory exercises for various courses are being developed to illustrate underlying biological principles related to major health problems in Black Americans. These activities include electrophoresis of normal and sickle cell hemoglobin, fluorescent antibody demonstration of proteins associated with Graves disease and sickle cell patients, cardiovascular system activities related to hypertension in Black Americans, and biochemical tests to illustrate diabetes, lactose intolerance, and glucose-6-phosphate dehydrogenase (G6PD) deficiency. Four student stations for electrophoresis experiments, biochemical studies and microscopic work are being set up. In addition, two analytical balances, two pH meters, two variable speed centrifuges, one inverted phase microscope, one fluorescent phase video microscope for class demonstration, and one transfer hood are being installed. Capabilities for the hypertension studies already are available. The project motivates all students, especially minorities, to maintain their efforts in pursuing a biomedically-related career. In addition, the laboratory activities developed will be made available as a laboratory manual for other institutions. The grantee institution is matching the NSF award with an equal sum obtained from non-Federal sources.