Sex-specific susceptibility windows for fetal origins of adult disease and transgenerational effects

成人疾病胎儿起源和跨代效应的性别特异性易感性窗口

• 批准号: 280203
• 负责人: Trasler Jacquetta M
• 金额: $ 63.23万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-03-01 至 2018-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=280203&lang=en
• 关键词: Dna Methylation; Epigenetic; Fetus; Folate; Germ Cells; Sex-Specific; Transgenerational

The prenatal period is a key time of fetal programming. In particular, one of the tissues of the fetus, the germ line, undergoes a genome-wide programming event that is critical for fertility of the resulting offspring and the health of future generations

产前是胎儿程序化的关键时期。特别是，胎儿的一个组织，生殖系，经历了全基因组编程事件，这对由此产生的后代的生育能力和后代的健康至关重要。