Understanding DNA damage signaling by the ubiquitin ligases RNF8 and RNF168
Understanding DNA damage signaling by the ubiquitin ligases RNF8 and RNF168
批准号:
278241
负责人:
Durocher Daniel
金额:
$74.49万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2018-03-01
中文摘要
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英文摘要
In this renewal, Dr. Durocher and his team proposes to build on their discovery of a cellular communication system, underpinned by the RNF8 and RNF168 proteins, that employ the small protein ubiquitin. This cellular signaling pathway orchestrates the ass
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