Rational design of array-based nanozyme sensors

基于阵列的纳米酶传感器的合理设计

• 批准号: DP230101650
• 负责人: Prof Vipul Bansal
• 金额: $ 18.86万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230101650
• 关键词: Rational; design; array; based; nanozyme

The project aims to obtain a deep understanding of molecular interactions at the nano-bio interface, and use this knowledge to develop a robust sensor technology for the rapid detection of foodborne pathogens in complex samples. The project proposes to employ an innovative approach that mimics the senses of smell and taste, where an array of aptamers are expected to work in synergy to precisely identify a target, providing an edge over current sensing technologies. Expected outcomes include a ready-to-go analytical tool for the detection of food contaminants. This should provide significant economic, health, and social benefits through supporting Australian food and health sectors, and the potential commercialisation of sensor technologies.

该项目旨在深入了解纳米生物界面的分子相互作用，并利用这些知识开发一种强大的传感器技术，用于快速检测复杂样品中的食源性病原体。该项目建议采用一种创新的方法，模仿嗅觉和味觉，其中一系列适体预计将协同工作，以精确识别目标，提供优于当前传感技术的优势。预期成果包括用于检测食品污染物的现成分析工具。这将通过支持澳大利亚食品和卫生部门以及传感器技术的潜在商业化，提供重大的经济，健康和社会效益。