Single Electron Transfer. A Major Reaction Pathway in Organic Chemistry

单电子转移。

• 批准号: 8914309
• 负责人: Eugene Ashby
• 金额: $ 35.7万
• 依托单位: Georgia Tech Research Corporation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-12-15 至 1994-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8914309&HistoricalAwards=false
• 关键词: Single; Electron; Transfer.; Major; Reaction

In this project ("Single Electron Transfer. A Major Reaction Pathway in Organic Chemistry") in the Organic Dynamics Program of the Chemistry Division, Professor Eugene C. Ashby will study single electron transfer reactions. The main thrust of the work is the gathering of experimental evidence to support the proposition that single electron transfer is a major pathway in organic chemistry. Professor Ashby will perform experiments with various alkyl halide model substrates in an attempt to discern the electron transfer nature of nucleophilic aliphatic substitution reactions. These studies will involve comparison of rate and stereochemistry as a function of leaving group. Competing radical, carbanion, and carbene intermediates in the reactions of primary alkyl halides with lithium diisopropylamide are also being investigated. Professor Ashby is also studying the mechanism of conjugate addition of metal alkyls to enones under a wide variety of experimental conditions using the probe of isomerization of the cis enone to the trans enone.

在这个项目中（“单电子转移。 第1001章大反应 有机动力学课程（Pathway in Organic Dynamics Program） 化学系的尤金C.阿什比将学习 单电子转移反应 的主旨 工作是收集实验证据，以支持 单电子转移是一个主要的途径， 有机化学 阿什比教授将用各种烷基 卤化物模型衬底，试图辨别电子 脂族亲核取代转移性质 反应. 这些研究将涉及比较率和 立体化学作为离去基团的函数。 竞争 自由基、负碳离子和卡宾中间体 伯烷基卤化物与二异丙基氨基锂的反应， 正在调查 阿什比教授也在研究 烷基金属与烯酮的共轭加成机理 各种各样的实验条件下使用的探针 顺式烯酮异构化为反式烯酮。