Chemistry of Singlet Oxygen and Related Topics

单线态氧化学及相关主题

• 批准号: 8914366
• 负责人: Christopher Foote
• 金额: $ 49.65万
• 依托单位: University of California-Los Angeles
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-01-01 至 1994-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8914366&HistoricalAwards=false
• 关键词: Chemistry; Singlet; Oxygen; Related; Topics

In this project in the Organic Dynamics Program, Professor Christopher S. Foote will study the "Chemistry of Singlet Oxygen and Related Topics" in the Chemistry Department at the University of California, Los Angeles (UCLA). He will explore the biological aspects, chemistry, photochemistry, and spectroscopy of singlet oxygen. The chemistry of singlet oxygen is of tremendous pathologic, therapeutic, and industrial significance to a society vitally dependent on atmospheric oxygen and sunlight for its existence. Photooxidation plays a major role in the degradation of materials and in a number of pathological processes. Photooxygenations involving singlet oxygen and electron transfer are being studied, with the goal of elucidating the borderlines for various mechanisms. Mechanistic tests are being developed for intermediates in these reactions such as exiciplexes, zwitterions, and perepoxides. Isotope effects, trapping experiments, and direct time-resolved spectroscopic probes for intermediates are being used, and novel unstable products of some reactions are being characterized at low temperatures.

在有机动力学计划的这个项目中，Christopher S. Foote教授将在加州大学洛杉矶分校化学系研究“单线态氧的化学及相关主题”。他将探索单线态氧的生物学方面、化学、光化学和光谱学。单线态氧的化学性质对一个严重依赖大气氧气和阳光生存的社会具有巨大的病理、治疗和工业意义。光氧化在材料降解和许多病理过程中起着重要作用。人们正在研究单线态氧和电子转移的光氧化作用，目的是阐明各种机制的边界。对于这些反应的中间体，如异构体、两性离子和过氧化物，正在开发机械试验。同位素效应、捕获实验和直接时间分辨光谱探针被用于中间体，一些新的不稳定反应产物在低温下被表征。