Targeting the PD-1 signaling pathway to rescue HIV T cell dysfunction
Targeting the PD-1 signaling pathway to rescue HIV T cell dysfunction
批准号:
185176
负责人:
Tanel Andre
金额:
$7.1万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-02-01 至 2011-04-01
中文摘要
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英文摘要
A hallmark of HIV infection is the dysfunction of HIV specific CD4+ and CD8+ T cells. These cells show impairment of cytokine production, decrease in their proliferative potential and cytolytic activities. T cell exhaustion, characterised by the presence
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