Biomechanical Foundation of Tissue Engineering of Arteries and Veins

动静脉组织工程生物力学基础

• 批准号: 8917576
• 负责人: Yuan-Cheng Fung
• 金额: $ 24万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-03-01 至 1995-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8917576&HistoricalAwards=false
• 关键词: Biomechanical; Foundation; Tissue; Engineering; Arteries

The goal of this proposal is to improve the understanding of the growth and resorption of blood vessels in response to stresses and strains in the vessel wall. The work includes a) experimental and theoretical work to relate structural and mechanical parameters of the wall to stresses and strains, b) determination of factors that determine growth and resorption, and c) determination of the relationship between stress and growth. The work will provide new fundamental knowledge about the way tissues respond to mechanical intervention. The research strongly depends on advanced engineering techniques to describe tissue characteristics, and should contribute to the developing field of "tissue engineering".

本提案的目的是增进对 血管的生长和吸收 血管壁的应力和应变。 工作 包括a）实验和理论工作， 墙的结构和力学参数， 应力和应变，B）确定 确定生长和再吸收，以及c）确定 压力和生长的关系。 这项工作将 提供了关于组织 应对机械干预。 研究强烈 依靠先进的工程技术来描述 组织特征，并应有助于 发展中的“组织工程”领域。