Inherited susceptibility to cancer: from gene discovery to mechanisms to clinical applications

遗传性癌症易感性：从基因发现到机制再到临床应用

• 批准号: 332440
• 负责人: Foulkes William D
• 金额: $ 184.57万
• 依托单位: CIUSSS de Centre-Ouest-de-l'Ile-de-Montral-Jewish General
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=332440&lang=en
• 关键词: Dicer1; Founder Mutations; Genetic Predisposition; Hereditary Cancer; Multiple Primary Tumors; Rare Tumours

Cancer is a common disease which is typically the result of genetic changes that lead to aberrant growth and behaviour of affected cells, which then produce tumours which can spread throughout the body. Some individuals are at higher risk for cancer becau

癌症是一种常见的疾病，通常是遗传变化的结果，导致受影响细胞的异常生长和行为，然后产生可以扩散到全身的肿瘤。有些人患癌症的风险较高，因为