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Exploring the influence of DICER1 mutations on the mTOR signalling pathway

Exploring the influence of DICER1 mutations on the mTOR signalling pathway
探讨 DICER1 突变对 mTOR 信号通路的影响
批准号：
344858
负责人：
Foulkes William D
金额：
$69.62万
依托单位：
Lady Davis Institute for Medical Research (Mtl)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2021-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=344858&lang=en
关键词：
Dicer1 Gene Expression Gene Silencing Metabolism Microrna Mtor Neoplasm

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中文摘要
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英文摘要
The DICER1 syndrome is caused by inherited mutations in the gene DICER1. Mutation carriers are at increased risk of developing a variety of rare tumours early in life. The DICER1 gene product is an enzyme which functions by cutting small molecules called
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会议论文
Inherited susceptibility to cancer: from gene discovery to mechanisms to clinical applications
Third International Symposium on Hereditary Breast and Ovarian Cancer
  • 批准号：
    187406
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $1.46万
  • 财政年份：
    2009
  • 负责人：
    Foulkes William D
  • 依托单位：
    Undetermined
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