International Workshop on Molecular Approaches to Development in Dictyostelium, Turin, Italy, Sept. 9-15,1990

发展分子方法国际研讨会，盘基网柄菌，意大利都灵，1990 年 9 月 9-15 日

• 批准号: 8921463
• 负责人: William Loomis
• 金额: $ 1.86万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-04-01 至 1991-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8921463&HistoricalAwards=false
• 关键词: International; Workshop; Molecular; Approaches; Development

This award will support an international workshop on molecular approaches to development in the amoebal organism Dictyostelium to be held in Turin, Italy from September 9 to September 15, 1990. The meeting, organized by Prof. William F. Loomis of the University of California-San Diego and Prof. Salvatore R. Bozzaro of the University of Turin, will focus on three topics: (1) Signals and signal transduction mechanisms that affect gene expression; (2) Transcriptional and post-transcriptional control mechanisms; (3) Modifications of specific proteins and their relations to cellular functions. The various applications of advanced techniques to diverse aspects of the differentiations that occur in Dictyostelium discoideum have been fruitful in gaining a global understanding of the mechanisms by which a group of genetically and physiologically identical cells can interact and diverge into specialized cell types. The advent of powerful molecular genetic techniques applicable to this system has opened up many new avenues that are leading to insights relevant not only to Dictyostelium development but also to related processes that occur in all multicellular organisms, especially during embryogenesis. Advances in the understanding of complex processes in Dictyostelium have benefitted significantly from the periodic exchange of techniques, results and points of view between laboratories at international meetings. Hosting this meeting in Italy ensures the participation of the most active Italian and Western Europe laboratories and will facilitate the rapid dissemination of new data and foster international collabora- tions.

这一奖项将支持将于1990年9月9日至9月15日在意大利都灵举行的关于变形虫有机体Dictyostelials分子发育方法的国际研讨会。这次会议由加州大学圣地亚哥分校的威廉·F·卢米斯教授和都灵大学的塞尔瓦托·R·博扎罗教授组织，将集中讨论三个主题：(1)影响基因表达的信号和信号转导机制；(2)转录和转录后控制机制；(3)特定蛋白质的修饰及其与细胞功能的关系。在盘基网柄菌分化的不同方面，先进技术的不同应用取得了丰硕的成果，获得了对一组遗传和生理上相同的细胞群相互作用并分化为特殊细胞类型的机制的全球理解。可应用于这一系统的强大的分子遗传学技术的出现开辟了许多新的途径，这些途径不仅与网柄金藻的发育有关，而且还与所有多细胞生物体中发生的相关过程有关，特别是在胚胎发生期间。在国际会议上，实验室之间定期交流技术、结果和观点，大大有助于对网柄基盘基菌复杂过程的理解。在意大利主办这次会议确保了最活跃的意大利和西欧实验室的参与，并将促进新数据的迅速传播和促进国际合作。