Calcium Ion Resonance In Bone Cells

电磁场（EM）已被广泛应用于 试图改善骨骼愈合，但 该地区仍有争议。 的原因之一 有争议的是， 场对骨细胞的影响尚不清楚。 这一拟议 项目是检查是否离子回旋共振， 导致特定离子的膜转运改变， 可能是骨骼功能改变的机制 具体来说，这项工作将检查是否钙离子 由于回旋共振， 电磁场引起的，以及这种影响是否是 这取决于所施加的场的大小。 这是一项基础研究， 最终改进工程方法的意义 通过该方法EM刺激用于改善骨愈合。

Electromagnetic (EM) fields have been used quite extensively in an attempt to improve bone healing, but the area remains controversial. One of the reasons for the controversy is that the basic mechanism by which EM fields affect bone cells is not known. This proposed project is to examine whether ion cyclotron resonance, leading to altered membrane transport of specific ions, might be the mechanism of altered bone function. Specifically, this work will examine whether calcium ion transport is enhanced as a result of cyclotrone resonance induced by EM fields, and whether this effect is dependent on the magnitude of the applied fields. This is a fundamental study that may have great significance for eventually improving engineering methods by which EM stimulation is used to improve bone healing.