Identification of causal variants for complex traits
Identification of causal variants for complex traits
批准号:
DP230101352
负责人:
Prof Michael Goddard
金额:
$38.04万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2023
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2023-01-01 至 2025-12-31
中文摘要
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英文摘要
The aim of this project is to identify causal variants for complex traits in cattle and humans. Although most important traits in agriculture, medicine and evolution are complex traits, very few of the genetic variants affecting these traits are known and this undermines our understanding of how genetic variants affect a trait and practical uses of this knowledge. Huge datasets of individuals with genome sequence and phenotypes and new statistical methods provide the opportunity to close this gap. The outcome will be identification of many genomic variants causing variation in complex traits. This will benefit scientific understanding of complex traits and the ability to predict traits for individuals from their genome sequence.
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会议论文
Prediction of phenotype for multiple traits from multi-omic data
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批准号:DP200100499
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项目类别:Discovery Projects
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资助金额:$29.15万
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财政年份:2020
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负责人:Prof Michael Goddard
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依托单位:
The extent, causes and implications of pleiotropy among complex traits
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批准号:DP160101056
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项目类别:Discovery Projects
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财政年份:2016
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负责人:Prof Michael Goddard
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依托单位:
The genetic architecture and evolution of quantitative traits
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批准号:DP130100563
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项目类别:Discovery Projects
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资助金额:$19.19万
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财政年份:2013
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负责人:Prof Michael Goddard
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依托单位:
Explaining the Dark Matter of Genome-wide Association Studies for Complex Disease
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批准号:nhmrc : 613672
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项目类别:NHMRC Project Grants
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资助金额:$30.21万
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财政年份:2010
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负责人:Prof Michael Goddard
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依托单位:
Why is most of the genetic variance for complex traits undetected by large powerful screens of common variants?
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批准号:DP1093502
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项目类别:Discovery Projects
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资助金额:$25.08万
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财政年份:2010
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负责人:Prof Michael Goddard
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依托单位:
国内基金
海外基金
使用倾向分(Propensity Score)和主分层(Principal Stratification)进行因果推断
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批准号:10401003
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项目类别:青年科学基金项目
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资助金额:11.0万元
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批准年份:2004
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负责人:张俊妮
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依托单位: