Presidential Young Investigator/New Linear-Chain Compounds with Metal Carbonyl Repeat Units

总统青年研究员/具有金属羰基重复单元的新型直链化合物

• 批准号: 8958027
• 负责人: Cynthia Schauer
• 金额: $ 20.75万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-01 至 1995-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8958027&HistoricalAwards=false
• 关键词: Presidential; Young; Investigator; New; Linear

This Presidential Young Investigator award from the Inorganic, Bioinorganic and Organometallic Chemistry Program will support the research of Dr. Cynthia K. Schauer in organometallic and bioinorganic chemistry. The binding of vanadate and polyvanadate anions to cationic metal complexes will be explored, together with the chemistry and electrochemistry of the resulting metal-vanadate complexes. The results are expected to provide a better understanding of the mechanism of the inhibition of a variety of phosphatase enzymes, in which the vanadate anion is believed to replace phosphate at a catalytic site at which it is bound to a metal cation. A second facet of the research program will involve the application of metal cluster chemistry to the synthesis of new solid state materials. Heteroatom-substituted metal carbonyl clusters will be synthesized such that the desired composition is attained after removal of carbon monoxide by thermal, laser-induced or electron-beam induced decomposition. This approach is expected to provide new solid materials without the need for high-temperature treatment, and allow the synthesis of materials which are unstable at high temperatures.

这位来自无机物的总统青年研究员奖， 生物无机和有机化学计划将支持 辛西娅·K博士的研究Schauer在有机金属和 生物无机化学钒酸盐的结合， 将多钒酸盐阴离子转化为阳离子金属络合物， 探索，连同化学和电化学， 得到的金属-钒酸盐络合物。结果 希望能更好地了解 抑制多种磷酸酶，其中 钒酸根阴离子被认为以 催化位点，在该催化位点处其与金属阳离子结合。第二 研究计划的一个方面将涉及以下方面的应用 金属簇合物化学合成新的固态 材料.杂原子取代的金属羰基簇将 从而获得所需的组成 在通过热、激光诱导或 电子束诱导分解这一做法预计 提供新的固体材料， 高温处理，并允许合成 在高温下不稳定的材料。