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Membrane receptors, microenvironment Proteinases and signaling: Therapeutic targets for inflammatory disease and cancer.

Membrane receptors, microenvironment Proteinases and signaling: Therapeutic targets for inflammatory disease and cancer.
膜受体、微环境蛋白酶和信号传导：炎症性疾病和癌症的治疗靶点。
批准号：
343307
负责人：
Hollenberg Morley D
金额：
$122.8万
依托单位：
University of Calgary
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2021-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=343307&lang=en
关键词：
Atopic Dermatitis Bladder Cancer Colitis G-Protein-Coupled Receptors Inflammatory Disease Atopic Dermatitis Metastasis Microenvironment Proteases Molecular Pharmacology Protease-Activated Receptors Signal Transduction

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英文摘要
The tissue environment of inflammatory diseases like arthritis & cancer is known to produce increased amounts of digestive enzymes. Our published work to date has uncovered a cell signaling mechanism (proteinase-activated receptors, or PARs) that is drive
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Membrane Receptors and Hormone Action: Proteinase-mediated signaling
  • 批准号：
    222877
  • 项目类别：
    Operating Grants
  • 资助金额：
    $67.17万
  • 财政年份：
    2011
  • 负责人：
    Hollenberg Morley D
  • 依托单位：
    University of Calgary
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