Studies of Structure and Conformation Using NMR Spectroscopyand X-Ray Crystallography

使用核磁共振波谱和 X 射线晶体学研究结构和构象

• 批准号: 9005618
• 负责人: Eric Noe
• 金额: $ 25万
• 依托单位: Jackson State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-10-01 至 1994-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9005618&HistoricalAwards=false
• 关键词: Studies; Structure; Conformation; Using; NMR

The proposed research consists of four parts, as follows: (1) NMR studies of cyclopropyl conjugation, for comparing the - donating abilities of the three-membered ring, double bond, and phenyl group; also studies expected to show that negatively-charged divalent phosphorus can be an effective -electron donor; (2) 2-D NMR studies of structure and dynamics for thioureas aimed at elucidating conformational equilibria and associative phenomena; (3) Synthesis and X-ray structural determination of novel organometallic compounds having two metal atoms joined by a ligand attached to one metal as a -arene ligand, and attached to the second ligand by a lone pair of electrons; (4) Formation of metal-carbon bonds on group 6 elements containing metal-oxo groups; the newly synthesized complexes are expected to show an interaction between the oxo and alkyl groups and a possibility exists of a transfer reaction of oxygen to an alkyl ligand. The four projects will make extensive use of NMR spectroscopy and X-ray crystallography. Multinuclear variable temperature one- and two-dimensional NMR experiments will allow analysis of exchange, structure and conformations of organic and organometallic compounds. In addition, the structure of the organometallic complexes synthesized will be determined by X-ray crystallography. The projects will provide minority students with experience in using both methods of assigning structure and conformation and in the study of chemical and magnetization exchange.//

拟议的研究包括以下四个部分： (1)环丙基缀合的NMR研究，用于比较 三元环的供电子能力， 双键和苯基;预计研究还将 显示带负电荷二价磷可以是 有效电子给体的二维核磁共振研究 硫脲的结构和动力学，旨在阐明 构象平衡和缔合现象;（3） 新化合物的合成及X-射线结构测定 有机金属化合物，具有两个金属原子，通过 连接到一种金属上的配体作为-芳烃配体，和 通过孤对电子连接到第二配体; (4)第6族元素上金属-碳键的形成 含有金属氧代基团;新合成的 预计复合物将显示出 氧代和烷基基团，并且可能存在 氧向烷基配体的转移反应。 这四个项目将广泛使用核磁共振技术 光谱学和X射线晶体学。 多核 变温一维和二维核磁共振 实验将允许分析交换，结构和 有机和有机金属化合物的构象。 在 此外，有机金属配合物的结构 将通过X射线晶体学确定合成的晶体的量。 这些项目将为少数民族学生提供 具有使用两种分配结构方法的经验 和构象，并在化学和 磁化交换。