Electric Dipole Moments of Chiral Ion Pairs

这个女性职业发展研究机会奖是在有机化学的一般领域。韦尔斯利学院化学系的Margaret V. Merritt博士将开发使用电偶极矩测量来检查手性离子对的结合和结构的方法。特定溶剂中离子对的离子间几何形状可能与电偶极矩有关。在本研究中，两个离子都有一个不对称中心：阳离子将是季胺，阴离子将是扁桃酸盐。电容和电导测量将在布兰代斯大学名誉教授欧内斯特·格伦沃尔德博士的建议下进行，他在这一领域有经验。1名博士后和1名本科生参与。该奖项将使Merritt博士能够建立一种新的能力，这是她之前进行的动力学研究的补充。预计本科生将能够很容易地参与这些新项目。未来的学生项目将包括制备和表征新的手性离子对，以及确定单个离子对偶极矩的溶剂依赖性。红外和质子核磁共振光谱和x射线结构表征也将被利用。

This Research Opportunities for Women Career Advancement Award is in the general area of organic chemistry. Dr. Margaret V. Merritt of the Chemistry Department at Wellesley College will develop methods for using electric dipole moment measurements to examine the association and structure of chiral ion pairs. The interionic geometry of ion pairs in particular solvents may be correlated with the electric dipole moment. In this study, both of the ions will have an asymmetric center: the cation will be a quaternary amine and the anion will be the salt of mandelic acid. The capacitance and conductance measurements will be made with the advice of Dr. Ernest Grunwald, emeritus professor of Brandeis University, who has experience in this field. A postdoctoral worker and an undergraduate student will participate in the project. This award will enable Dr. Merritt to establish a new capability that is complementary to kinetic studies she has carried out previously. It is anticipated that undergraduate students will be able to participate readily in these new projects. Future student projects will involve the preparation and characterization of novel chiral ion pairs and determination of the solvent dependence of the dipole moment of a single ion pair. Infrared and proton nmr spectroscopy and X-ray structure characterization will also be utilized.