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Mitochondrial DNA Divergence Among Chromosomal Species of Aotus

Mitochondrial DNA Divergence Among Chromosomal Species of Aotus
Aotus 染色体种类之间的线粒体 DNA 分歧
批准号:
9008896
负责人:
Mary Ashley
金额:
$1.18万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1990
资助国家:
美国
项目状态:
已结题
起止时间:
1990-06-15 至 1991-11-30

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中文摘要
翻译
这项研究将调查遗传差异, 猫头鹰猴物种间的系统发育关系, Aotus 猫头鹰猴广泛分布于中南 美国参考 直到十年前,人们还普遍认为猫头鹰 猴是一个单一的物种,A.三弗吉尼亚。 更 然而,最近有人提出, 代表了至少十种具有不同 地理分布,可以区分为 表型和基因型。 Aotus经历了一个 二倍体染色体异常核型变化 计数范围从46到58,但其他基因的变化 人物尚未被调查。 这项研究将 检测线粒体DNA(mtDNA)及相关基因 在几个核型不同的 物种 这项工作是重要的,因为使用猫头鹰 猴子作为疟疾研究的模型, 这一属中染色体重排的不寻常性质。
英文摘要
This research will investigate genetic divergence and phylogenetic relationships among species of the owl monkey, Aotus. Owl monkeys are widely distributed in Central and South America. Until ten years ago it was generally assumed that owl monkeys comprised a single species, A. trivirgatus. More recently, however, it has been suggested that the owl monkey represents at least ten allopatric species which have distinct geographic distributions and can be distinguished both phenotypically and genotypically. Aotus has undergone an extraordinary amount of karyotypic change with diploid chromosome counts ranging from 46 to 58, but changes in other genetic characters have not yet been investigated. This research will examine mitochondrial DNA (mtDNA) and several related gene sequences within and among several karyotypically distinct species. This work is important because of the use of the owl monkey as a model for malarial research, and because of the unusual nature of chromosomal rearrangements in this genus.
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