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The effects of a paternal folate deficiency in a transgenic mouse model representative of a vulnerable population

The effects of a paternal folate deficiency in a transgenic mouse model representative of a vulnerable population
父系叶酸缺乏对代表弱势群体的转基因小鼠模型的影响
批准号：
367227
负责人：
Lismer Ariane
金额：
$1.27万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-12-01 至 2017-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367227&lang=en
关键词：
Birth Defects Complex Diseases Environmental Stressors Folate Deficient Diet Histone Modifications Metabolism Paternal Epigenetic Inheritance Sperm Epigenome Transgenerational Epigenetics Vulnerable Populations

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中文摘要
翻译
男女弱势群体对糖尿病和精神疾病等复杂疾病的易感性增加，他们的子女患病风险也更大，出生缺陷和死婴的比率也更高。完毕
英文摘要
Vulnerable populations of men and women have increased susceptibility to complex diseases such as diabetes and mental illness, their children are also at greater risk for disease and there exists higher rates of birth defects and still-born children. Over
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Deciphering the molecular routes by which an altered sperm epigenome elicits birth defects in the offspring
  • 批准号：
    416919
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2019
  • 负责人：
    Lismer Ariane
  • 依托单位：
    McGill University
海外基金