U.S.-Bulgaria Research on Biopolymers Using The Exciton Chirality Method

这项美国和保加利亚研究的主要目标是 哥伦比亚大学的中西浩二博士 和保加利亚研究所的尼娜·贝罗娃博士 有机化学是研究生物聚合物使用 激子手性方法。 果胶将被用于 糖苷的全面分类和测定 联动 在他们的工作中，研究人员打算 开发并使用一套新的花青染料， 生物碱的绝对构型用氨基表示 和氨基糖。 （这些染料是为独特的 光谱特性，仅需纳克样品 数量。） 预计结果将扩大 确定复合物微观结构的方法， 不规则的多糖如果胶， 用于确定 少量的稀有糖， 糖苷键中的分支点。 这个有机化学项目完成了这个项目 促进科学知识的目标， 美国和东部的主要研究人员 欧洲将联合收割机互补人才， 共同感兴趣领域的研究资源 和能力。

The primary objective of this US-Bulgaria research project between Dr. Koji Nakanishi of Columbia University and Dr. Nina Berova of The Bulgarian Institute of Organic Chemistry is to examine biopolymers using exciton chirality methods. Pectins will be featured for overall classification and determination of glycosidic linkages. In their work, the researchers intend to develop and employ a new set of cyanine dyes that react with amino groups for absolute configuration of alkaloids and amino sugars. (These dyes are chosen for unique spectroscopic properties, requiring only nanogram sample quantities.) Results are expected to extend the methodology for determining microstructure of complex, irregular polysaccharides such as pectin and would allow for the determination of absolute configurations of small amounts of rare sugars and the frequency and points of branching in glycosidic linkages. This project in organic chemistry fulfills the program objective of advancing scientific knowledge by enabling leading researchers in the United States and Eastern Europe to combine complementary talents and pool research resources in areas of strong mutual interest and competence.