Dinuclear Oxo-Iron Complexes of Polyimidazole Ligands

聚咪唑配体的双核氧代铁配合物

• 批准号: 9016947
• 负责人: Robert Buchanan
• 金额: $ 14.18万
• 依托单位: University of Louisville Research Foundation Inc
• 依托单位国家: 美国
• 项目类别: Continuing grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-01-15 至 1994-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9016947&HistoricalAwards=false
• 关键词: Dinuclear; Oxo; Iron; Complexes; Polyimidazole

In this project in the Inorganic, Bioinorganic, and Organometallic Program of the Chemistry Division, Buchanan will prepare synthetic analogues of the active sites of non-heme oxo-iron proteins. These proteins are capable of functions ranging from oxygen transport and activation to phosphate ester hydrolysis, yet little structural information about them is firmly established. New oxo-bridged diiron complexes containing polyimidazole ligands will be synthesized and characterized. Physical methods will include X-ray crystallography, electrochemical measurements, electronic spectroscopy, magnetic and Mossbauer studies, EPR, and NMR. The binding of dioxygen, hydro- peroxide, and selected anions to the models containing open coordination sites will be examined. The oxygenase chemistry of the binuclear complexes towards alkanes will be explored.

在这个项目中，无机，生物无机， 化学部的有机物计划，布坎南将 制备非血红素活性位点的合成类似物 含氧铁蛋白 这些蛋白质能够发挥 从氧的运输和活化到磷酸酯 水解，但很少有关于它们的结构信息， 牢固确立。 含多咪唑的新型氧桥二铁配合物 将合成和表征配体。 物理 方法将包括X射线晶体学，电化学 测量、电子光谱、磁性和穆斯堡尔 研究，EPR和NMR。 分子氧，氢- 过氧化物和选定的阴离子的模型含有开放 将检查协调地点。加氧酶化学 探讨了与烷烃形成双核配合物的可能性。