Construction of a High-Resolution (10 nanometer) Optical Microscope Using the LAMDA Effect
Construction of a High-Resolution (10 nanometer) Optical Microscope Using the LAMDA Effect
批准号:
9017024
负责人:
Alan Bearden
金额:
$65.0万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1990
资助国家:
美国
项目状态:
已结题
起止时间:
1990-09-15 至 1993-08-31
中文摘要
利用最近发现的效应(激光放大运动检测和分析,LAMDA),本项目将开发一个分辨率为10nm的远场光学显微镜。这种分辨率是可见光波长的五十分之一,大约是以前光学显微镜所获得的分辨率的二十分之一,它将允许对光学显微镜从未实现过的细节进行成像。LAMDA显微镜将能够实时直接观察生物实体,如dna -蛋白质复合物,细胞生长因子在发育过程中的出现,有丝分裂的结构细节,以及生物膜中通道形成蛋白的结构细节。进一步的应用将包括所有的科学、工程、半导体和磁性数据存储行业的过程控制,事实上,任何具有前所未有的高分辨率的光学显微镜都可以发挥价值。
英文摘要
Using a recently discovered effect (Laser Amplified Motion Detection and Analysis, LAMDA), this project is to develop a far- field optical microscope with a resolution of 10nm. This resolution, one-fiftieth of the wavelength of visible light and about one-twentieth of the resolution obtained by previous optical microscopes, would permit the imaging of detail never before realized with an optical microscope. The LAMDA microscope would be capable of making directly observable, in real time, such biological entities as DNA-protein complexes, the emergence of cell-growth factors in development, the structural details underlying mitosis, and of channel-forming proteins in biological membranes. Further applications would encompass all of the sciences, engineering, process control in the semiconductor and magnetic data storage industries, in fact wherever light microscopy of unprecedented high resolution can be of value.
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专著(0)
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会议论文
Development of Laser Feedback Microscopy (LFM): High- Resolution Optical Imaging for Biological Science and Technology
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批准号:9220661
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项目类别:Continuing Grant
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资助金额:$33.08万
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财政年份:1993
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负责人:Alan Bearden
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依托单位:
Preliminary Experiments on LAMDA Effect Microscopy
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批准号:9014834
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项目类别:Standard Grant
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资助金额:$5.0万
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财政年份:1990
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负责人:Alan Bearden
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依托单位:
Epr Studies of Chloroplast Photosynthesis
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批准号:7822245
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项目类别:Continuing Grant
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资助金额:$14.7万
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财政年份:1979
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负责人:Alan Bearden
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依托单位:
Chloroplast Photosynthesis
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批准号:7602968
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项目类别:Continuing Grant
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资助金额:$13.19万
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财政年份:1976
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负责人:Alan Bearden
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依托单位:
国内基金
海外基金
基于Resolution算法的交互时态逻辑自动验证机
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批准号:61303018
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项目类别:青年科学基金项目
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资助金额:22.0万元
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批准年份:2013
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负责人:章岚
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依托单位: