Construction of a High-Resolution (10 nanometer) Optical Microscope Using the LAMDA Effect

利用 LAMDA 效应构建高分辨率（10 纳米）光学显微镜

• 批准号: 9017024
• 负责人: Alan Bearden
• 金额: $ 65万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-09-15 至 1993-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9017024&HistoricalAwards=false
• 关键词: Construction; Resolution; 10; nanometer; Optical

Using a recently discovered effect (Laser Amplified Motion Detection and Analysis, LAMDA), this project is to develop a far- field optical microscope with a resolution of 10nm. This resolution, one-fiftieth of the wavelength of visible light and about one-twentieth of the resolution obtained by previous optical microscopes, would permit the imaging of detail never before realized with an optical microscope. The LAMDA microscope would be capable of making directly observable, in real time, such biological entities as DNA-protein complexes, the emergence of cell-growth factors in development, the structural details underlying mitosis, and of channel-forming proteins in biological membranes. Further applications would encompass all of the sciences, engineering, process control in the semiconductor and magnetic data storage industries, in fact wherever light microscopy of unprecedented high resolution can be of value.

使用最近发现的效应（激光放大运动 检测和分析，LAMDA），该项目是开发一个远- 场光学显微镜，分辨率为10 nm。 这 分辨率为可见光波长的五十分之一， 约二十分之一的分辨率获得以前的光学 显微镜，将允许成像的细节从来没有 用光学显微镜实现的。 LAMDA显微镜 能够在真实的时间内， 作为DNA-蛋白质复合物的生物实体， 细胞生长因子在发育过程中的结构细节 有丝分裂和通道形成蛋白在生物学中的作用 膜。 进一步的应用将包括所有 半导体科学、工程、过程控制和 磁性数据存储行业，事实上， 具有前所未有的高分辨率，这是有价值的。