The checkpoint receptor PD-1 inhibits Natural Killer cell responses to cancer.
The checkpoint receptor PD-1 inhibits Natural Killer cell responses to cancer.
批准号:
368560
负责人:
Ardolino Michele
金额:
$61.3万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01
中文摘要
人体有一个对付癌症的非凡武器:免疫系统。不幸的是,肿瘤经常学会如何逃避免疫反应。我们最近发现了这些机制之一,即抑制网络,抑制免疫细胞的种群。
英文摘要
The body has an extraordinary weapon against cancer: the immune system. Unfortunately, tumors often learn how to evade the immune response. We recently discovered one of these mechanisms, namely an inhibitory network that suppresses a population of immune
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会议论文
When the Killers become Thieves: NK cells are suppressed by trogocytosed PD-1.
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批准号:447611
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项目类别:Operating Grants
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资助金额:$21.86万
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财政年份:2021
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负责人:Ardolino Michele
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依托单位:
海外基金