Natural Killer (NK) Cells and Development of Atherosclerosis: Cellular and Molecular Mechanisms
Natural Killer (NK) Cells and Development of Atherosclerosis: Cellular and Molecular Mechanisms
批准号:
nhmrc : 1068500
负责人:
A/Pr Peter Tipping
金额:
$48.65万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
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英文摘要
Atherosclerosis, the accumulation of fat and white cells in the blood vessel wall is the major cause of heart attacks, stroke and death. Cholesterol lowering drugs reduce the risk by only 40%. Targeting cells that promote inflammation is one approach to further reduce risk. We have shown that a specific cell type called a natural killer (NK) cells contributes greatly to development of atherosclerosis. Our aim is to understand how these cells promote development of atherosclerosis.
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财政年份:2012
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批准号:nhmrc : 1030515
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财政年份:2012
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Role of B lymphocytes in atherosclerosis
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批准号:nhmrc : 1002333
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依托单位:
Atherosclerosis: Molecular action and suppression of NKT cell subsets
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财政年份:2007
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Gene Regulation, Cytokine regulation
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依托单位:
Pathogenic mechanisms of inflammatory diseases
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批准号:nhmrc : 334067
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Uncoupled Research Fellowship
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批准号:nhmrc : 194318
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项目类别:NHMRC Research Fellowships
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资助金额:$40.71万
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依托单位:
The Regulation of Organ Specific Inflammatory Disease
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依托单位:
Ongoing Uncoupled Research Fellowship
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批准号:nhmrc : 143806
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资助金额:$6.92万
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依托单位:
Contributions of intrinsic renal cells to inflammatory renal injury
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Initiation of inflammatory glomerular injury by extrinsic pathway activation
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依托单位:
海外基金