Asgard archaea: the first eukaryotic cells?

阿斯加德古菌：第一个真核细胞？

• 批准号: DP230100769
• 负责人: A/Prof Brendan Burns
• 金额: $ 42.58万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-07-02 至 2026-07-01
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230100769
• 关键词: Asgard; archaea; first; eukaryotic; cells

This project aims to uncover the role of unique microorganisms (Asgard archaea) in the origin of eukaryotes. These archaea may represent a ‘missing-link’ in eukaryotic evolution and are in abundance in the stromatolites in Shark Bay, Western Australia. Employing an innovative and interdisciplinary approach of cutting-edge molecular biology and high-resolution microscopy, this project expects to generate insights into fundamental aspects of evolution and cell biology. Expected outcomes include the discovery of unique branches of life and the proposal of new models for the emergence of eukaryotes. This research should allow for benefits across a spectrum of environmental and social gains, including improved ties with Indigenous communities.

该项目旨在揭示独特的微生物（Asgard古菌）在真核生物起源中的作用。这些古菌可能代表了真核生物进化中的“缺失环节”，并且在西澳大利亚州的东湾的基质层中大量存在。 采用尖端分子生物学和高分辨率显微镜的创新和跨学科方法，该项目预计将产生对进化和细胞生物学基本方面的见解。预期成果包括发现独特的生命分支和提出真核生物出现的新模式。这项研究应考虑到各种环境和社会收益，包括改善与土著社区的关系。