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An integrated strategy to identify inhibitors of protein-protein interactions as potential therapeutics for Parkinson's disease

An integrated strategy to identify inhibitors of protein-protein interactions as potential therapeutics for Parkinson's disease
确定蛋白质-蛋白质相互作用抑制剂作为帕金森病潜在疗法的综合策略
批准号：
380936
负责人：
Kalia Lorraine V
金额：
$104.77万
依托单位：
University Health Network (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-03-01 至 2023-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=380936&lang=en
关键词：
Alpha-Synuclein High-Throughput Screen Neurodegeneration Parkinson'S Disease Peptide Inhibitors Pooled Lentiviral Screen Protein Aggregation Protein-Protein Interactions Rat Model Yeast Model

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中文摘要
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英文摘要
Parkinson's disease is a common and disabling neurological disorder that is increasing in prevalence and thus having a growing impact on the Canadian population. The disease results from a process, called neurodegeneration, in which certain brain cells di
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Molecular mechanisms of neurodegeneration in Parkinson's disease
  • 批准号：
    374844
  • 项目类别：
    Salary Programs
  • 资助金额：
    $13.11万
  • 财政年份：
    2017
  • 负责人：
    Kalia Lorraine V
  • 依托单位：
    University Health Network (Toronto)
Molecular mechanisms of neurodegeneration in Parkinson's disease
  • 批准号：
    316310
  • 项目类别：
    Salary Programs
  • 资助金额：
    $21.86万
  • 财政年份：
    2014
  • 负责人：
    Kalia Lorraine V
  • 依托单位：
    University of Toronto
Identifying regulators of alpha-synuclein toxicity in dopaminergic neurodegeneration using a novel in vivo assay
  • 批准号：
    213570
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $12.57万
  • 财政年份：
    2010
  • 负责人：
    Kalia Lorraine V
  • 依托单位：
    University Health Network (Toronto)
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