Oxygen Chemistry: Reactivity and Activation of Dioxygen Species

将开展七个项目，专门确定二氧化氧物种的反应性及其活化方法。它们是：I)铁和钴络合物激活过氧化氢，II)铁络合物激活氧，III)金属络合物以配体为中心的氧化还原反应，IV)超氧化物的化学，V)细胞色素C氧化酶含血红素组分的模型的发展，VI)光系统II的锰辅助因子的模型的发展，和vii)对二氧化硫、氯和氯化芳香烃等亲电中心的过氧化物亲核性的表征。在化学部的无机、生物无机和有机金属项目中，德克萨斯农工大学的Donald T.Sawyer博士将继续研究氧、超氧化物和过氧化物的反应性和活性。这项工作将增加我们对生物氧化、燃烧过程和一些有害环境化学品(如氯代烃)的净化等不同主题的理解。

Seven projects devoted to determining the reactivity of dioxygen species and means of activating them will be pursued. These are: I) activation of peroxides by iron and cobalt complexes, II) activation of dioxygen by iron complexes, III) ligand centered redox reactions of metal complexes, IV) the chemistry of superoxide, V) development of a model for the heme containing component of cytochrome c oxidase, VI) development of a model for the manganese cofactor of photosystem II, and VII) the characterization of the nucleophilicity of peroxides towards electrophilic centers such as sulfur dioxide, chlorine, and chlorinated, aromatic hydrocarbons. %%% In this project in the Inorganic, Bioinorganic, and Organo- metallic Program of the Chemistry Division, Dr. Donald T. Sawyer of Texas A&M University will continue studies of the reactivity and activation of oxygen, superoxide, and peroxides. This work will increase our understanding of such diverse topics as biological oxidation, combustion processes, and decontamination of some environmentally hazardous chemicals such as chlorinated hydrocarbons.