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Waveguide-Mode-Enhanced Molecular Fluorescence and Other Aspects of the Dipole-Surface Problem

波导模式增强分子荧光和偶极子表面问题的其他方面

基本信息

批准号：
9107850
负责人：
Dennis Hall
金额：
$ 13.54万
依托单位：
University of Rochester
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
1992
资助国家：
美国
起止时间：
1992-03-15 至 1997-02-28
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=9107850&HistoricalAwards=false
关键词：
Waveguide Mode Enhanced Molecular Fluorescence

项目摘要

This research program investigates the physical origin of waveguide-mode-enhanced molecular fluorescence, a phenomenon first reported by the Principal Investigator and one of his former Ph.D. students (who jointly hold a patent on this process) in 1985. The patent has attracted the interest of the medical diagnostics industry. The term enhanced fluorescence refers to the substantial increase in the fluorescent signal emitted by a layer of molecules deposited onto a suitably prepared substrate compared to that from the same quantity of molecules deposited onto an unprepared substrate. In essence, a glass substrate can be dramatically improved as a substrate for molecular fluorescence by overcoating it with the proper combination of layers. Both optical scattering and optical waveguide modes contribute to the observed enhancement. The research attempts to develop a theoretical model of the enhancement process and to verify the predictions of the model through additional experiments. A proper quantitative description of the enhancement process will identify the optical properties of the sample that achieve the greatest enhancement. The proposed theoretical work applies to several other aspects of the dipole-surface problem important for optoelectronics, namely quantum-well vertical- cavity lasers and suppressed spontaneous emission. these problems are to be examined, but the primary emphasis of the research is waveguide-mode- enhanced molecular fluorescence.

这个研究项目调查了波导模式增强的分子荧光，这一现象最早是由校长调查员和他的一位前博士学生 (who在1985年，他们共同拥有这项技术的专利。这项专利引起了医学界的兴趣。诊断行业。术语增强荧光指的是荧光物质的大量增加，由沉积在其上的分子层发出的信号适当制备的基材与来自同样数量的分子沉积在无准备的衬底。本质上，可以显著改善作为基板，分子荧光，层的适当组合。双光散射和光波导模式有助于观察到增强。该研究试图建立一个理论模型，过程并验证模型的预测通过额外的实验。适当的增强过程的定量描述将确定样品的光学特性，实现最大的提升。理论工作适用于几个偶极面问题的其他重要方面对于光电子学，即量子阱垂直，腔激光器和抑制自发辐射。这些问题都有待研究，但主要的研究的重点是波导模，增强的分子荧光。